Figure 7.
Sera of NMO patients stimulates repair process. Quantitative PCR gene expression analysis of: (a) the expression of IL-15 increased significantly in astrocytes cultured with sera of NMO patients (1.1 ± 0.5, n = 31) vs. 0.72 ± 0.3 (n = 24) of astrocytes cultured with sera of HCs, (b) the expression of JAK-1 increased significantly in astrocytes cultured with sera of NMO patients (1.1 ± 0.4, n = 32) vs. 0.86 ± 0.4 (n = 24) of astrocytes cultured with sera of HCs. Each assay was repeated independently at least three times. Significance was determined by unpaired two-tailed student’s t-test (p * ≤ 0.05, *** ≤ 0.001). Error bars in all graphs represent standard deviation.