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Growth characteristics of cellular models for breast cancer.
| Endpoint | Cellular Model | |||
|---|---|---|---|---|
| 184-B5 | MCF-7 | 184-B5/HER | MDA-MB-231 | |
| AI Colony Formation | 0/18 | 18/18 | 18/18 | 18/18 |
| Incidence | 0% | 100% | 100% | 100% |
| Colony Number | ND | 30.9 ± 2.4 | 23.0 ± 2.6 | 38.9 ± 1.6 |
| Tumor Formation | 0/10 | 10/10 | 10/10 | 10/10 |
| Incidence | 0% | 100% | 100% | 100% |
| Latent Period (weeks) | 24 | 3–5 | 3–5 | 3–5 |
HER, human epidermal growth factor receptor; AI, anchorage-independent; ND, not detectable.
