Table 4.

Trends in clinical features of new tumor development in 482 patients presenting with solitary unilateral retinoblastoma

New tumor features	Age at development of each new tumor		Interval from diagnosis to development of each new tumor
	Incremental change per year	P	Incremental change per year	P
Tumor location, anteroposterior*	−6.9%	0.292	+31.6%	0.041
Tumor location, quadrantic	NA	0.625	NA	0.917
Basal dimension (mm)†	1.00	<0.001	0.51	0.406
Thickness (mm)†	0.55	0.001	0.56	0.146

*Expressed as percent change from postequatorial to preequatorial tumors per year, ^† Expressed as change in millimeters per year, Bold indicates statistical significance. NA: Not applicable