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. 2022 Jun 28;23(13):7181. doi: 10.3390/ijms23137181

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Association between genotypes of rs929039, rs9622682, and rs4820293 and IL-6 serum levels in early arthritis (EA) patients. Relationship between IL-6 serum levels (pg/mL) measured by ELISA in EA patients from PEARL study categorise by disease activity assessed by DAS28 score and the different genotypes of single nucleotide polymorphisms (SNPs) rs929039 (A), rs9622682 (B), rs4820293 (C) and genotype combination (D). Data are shown as interquartile range (p75 upper edge of box, p25 lower edge, p50 midline) as well as the p95 (line above box) and p5 (line below). Dots represent outliers. The statistical significance was determined with the multivariable analysis displayed in Table 2. The significance threshold was set at p < 0.05.