Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 30;23(13):7325. doi: 10.3390/ijms23137325

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The ontogeny of dendritic cells. This figure summarizes the pathways leading to dendritic cell (DC) development in the bone marrow and peripheral tissue. Differentiation of DCs is dependent on multiple cytokines and transcription factors. HSC, hematopoietic stem cell; CMP, common myeloid progenitor; MDP, macrophage–DC progenitor; CDP, common DC progenitor; CLP, common lymphoid progenitor; pre-cDC, classical/conventional DC progenitor; cDC1, type 1 classical/conventional DC; cDC2, type 2 classical/conventional DC; pDC, plasmacytoid DC; MoDC, monocyte-derived DC; FLT3L, FMS-like tyrosine kinase 3 ligand; CSF-1, colony-stimulating factor 1; IRF, interferon-regulatory factor; STAT3, signal transducer and activator of transcription 3; IL, interleukin.