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. 2022 Jun 30;23(13):7325. doi: 10.3390/ijms23137325

Figure 2.

Figure 2

Dendritic cell subsets and their markers, transcription factors, and functions. This figure summarizes the characteristics of the DC subsets. Each DC subset expresses unique markers and transcription factors. XCR1, X-C motif chemokine receptor 1; CLEC9A, C-type lectin domain containing 9A; ID2, inhibitor of DNA binding 2; NFIL3, nuclear factor, interleukin 3 regulated; ZBTB46, zinc finger and BTB domain-containing 46; SIRPα, signal regulatory protein alpha; RBPJ, recombination signal binding protein for immunoglobulin kappa J region; KLF4, Krüppel-like factor 4; TCF4, transcription factor 4; GM-CSF, granulocyte-macrophage colony-stimulating factor; BATF3, basic leucine zipper ATF-like 3 transcription factor; SIGLEC, sialic acid-binding Ig-like lectin; Ly6, lymphocyte antigen 6; CCR, C-C chemokine receptor; IFN, interferon; Th, helper T; Ag, antigen.