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. 2022 Jul 1;23(13):7359. doi: 10.3390/ijms23137359
Akt protein kinase B
CRM1 chromosomal region maintenance 1
Smac/DIABLO second mitochondria-derived activator of caspases/direct inhibitor of apoptosis-binding protein with low pI
EGFR, growth factor receptor
ESLD end stage liver disease
FoxO forkhead box O family of transcription factors
FoxO3 Forkhead box O3
CC hepatocellular carcinoma
H&E hematoxylin and eosin
HFD high fat diet
IVIS In vivo Imaging System
mTOR mammalian target of rapamycin
NAFLD Nonalcoholic fatty liver disease
NASH non-alcoholic steatohepatitis
NKA Na/K-ATPase
NMC standard mouse chow
NS normal saline
pAkt phosphorylated protein kinase B
pERK phosphorylated extracellular signal-regulated kinase
PI3K phosphatidylinositol-3-kinase
pSrc phosphorylation of Src kinase
PTEN phosphatase and tensin homolog deleted on Chromosome 10
RIPA buffer Radioimmunoprecipitation assay buffer
ROI reactive oxygen intermediates
siRNA Small interfering RNA
Smac second mitochondria-derived activator of caspases
Src Src kinase
S6K1 ribosomal protein S6 kinase beta-1
α1-Na/K-ATPase Na/K-ATPase Alpha1 subunit
α1-NKA-KND α1-NKA knock down HCC cell lines