The characteristics of macrophages (THP-1-derived cells) after the activation by media control (control) and the preparations from K. pneumoniae (Kleb) or C. albicans (Can) alone or the combination (Kleb+Can) as indicated by supernatant cytokines (IL-6, TNF-α, and IL-10) at 72 h post-incubation (A–C) and the gene expression (4 h post-incubation) of the molecules of inflammation (IL-6, TNF-α, IL-10, IL-8, NF-κB, and NOS2) (D–I). (Independent triplicated experiments were performed.) #, p < 0.05; ##, p < 0.01; ####, p < 0.0001 vs. control; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001, the indicated groups as have determined by ANOVA with Tukey’s analysis.