Figure 2.

The short-wavelength fundus autofluorescence (SW-FAF, left), near-infrared fundus autofluorescence (NIR-FAF, middle), and optical coherence tomography (OCT, right) of six patients with CD/CRD included in the study. For CIC09151, the NIR-FAF was not available and was replaced with a near-infrared reflectance image. Phenotypes may range from the focal central alterations (e.g., in CIC03862 CIC08066, CIC09067, CIC08918) to a progressively more extended disease (e.g., CIC09151, CIC02893, and CIC01418). Patients with similar ages may show different degrees of retinal degenerations. CIC09067 and CIC09151 are affected brothers that showed different phenotypes (CD and CRD, respectively) with different retinal involvement, despite sharing the same RPGR^ORF15 pathogenic variant and having the same age at the time of examination.