Table 1.

ELISA techniques to measure CSF total tau.

Antibodies	Publication	CSF Total Tau Increase in AD vs. Control
AT120 capturing antibody + polyclonal detection antibodies (rabbit anti-human tau antiserum)	Vandermeeren 1993 [23]	~100× AD (n = 27) 10.9 ± 4.9 pg/mL Control (n = 51) 0.1 ± 0.5 pg/mL
16B5 capturing antibody + 16G7 detection antibody	Vigo-Pelfrey 1995 [25]	~2× AD (n = 71) 361 ± 166 pg/mL Control (n = 26) 190 ± 80 pg/mL
Microsphere ELISA: polyclonal (anti-ht2) + monoclonal antibodies (F-F11 + F-H5)	Mori 1995 [24]	~2× AD (n = 14) 820 ± 90 pg/mL Control (n = 36) 380 ± 120 pg/mL
AT120 capturing antibody + HT7 detection antibody + BT2 detection antibody	Blennow 1995 [2]	~3× AD (n = 44) 524 ± 280 pg/mL Control (n = 31) 185 ± 50 pg/mL

AD = Alzheimer’s disease; CSF = cerebrospinal fluid; ELISA = enzyme-linked immunosorbent assay; pg/mL = picograms per milliliter.