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(A) Schematic of DOCK7 showing the relative location of the frameshift variant c.5391delA in Exon 42 (NM_001271999.1). DOCK homology domains DHR1 (amino acids 516–727) and DHR2 (amino acids 1668–2110) and TACC3-binding region (T-b). (B) Evolutionary conservation of the frameshift variant among 10 vertebrates.
