Figure 3.
The cryo-electron microscopy (cryo-EM) structure of human KCNQ4 and SsTx. Ribbon diagram of KCNQ4 atomic model (PDB id: 7VNP) with each of the four identical subunits color-coded, showing views from the bottom (A) and side (B). The key residues for the interaction with SsTx are labeled. The membrane-spanning helices and different subunits of KCNQ4 channel are indicated. (C): SsTx from Scolopendra morsitans. PDB id: 5X0S.