Figure 5.

Myeloid FcRn Cellular Expression is Elevated in PDAC Patients. Per-cell expression of FcRn quantified by analyzing the mean metal intensity (MMI; non-cancer, n = 8; PDAC, n = 13) (A) All MMI values were normalized and provided in a representative heatmap for each individual sample. In addition to immune populations from Figure 3A, subsets of T cells, monocytes, dendritic cells and MDSCs are presented. Quantified MMI plots of non-cancer (n = 8, black) and PDAC (n = 13, red) (B) T cells, (C) B cells, (D) granulocytes, (E) dendritic cells (F) monocytes, (G) MDSCs, and (H) NK cells. Box and whisker plots represent the median and interquartile range (25–75%) with whiskers representing the outlying 25%. All statistical comparisons are unpaired t-tests with a Welch’s correction.