Table 1.

Roadmap of the discovery of direct interactions of p21 with factors playing a role in DNA repair.

Year	Protein	Activity	DNA Repair System	Refs.
1994	PCNA	DNA synthesis	NER	[31,32,33,34,35,36]
1998	Ku70	damage recognition	NHEJ	[73]
2001	p300	KAT	NER	[56,58,59,60]
2003	PARP-1	synthesis of PAR	BER, SSBR	[66,67,68]
2006	p50 (POLD2)	subunit of DNA pol δ	(not reported)	[84]