Table 3.

Multivariate models of determinants of Phenodex Eye, Vascular and Cumulative scores in PXE. Serum T50 independently and inversely associated with ophthalmological, vascular and overall disease severity in PXE patients. SE—standard error. * p < 0.05.

Phenodex Eye (Final Model)	Parameter Estimates		p Value	Model Fitting
	Estimate	SE		Chi-square	p Value
				33.4	<0.001 *
Age	0.084	0.026	0.001 *
T50	−0.014	0.006	0.013 *
Serum fetuin-A	−0.25	0.13	0.044 *
Phenodex Vascular (Final Model)	Parameter Estimates		p Value	Model Fitting
	Estimate	SE		Chi-square	p value
				11.3	0.004 *
Arterial hypertension	1.42	0.69	0.039 *
T50	−0.010	0.004	0.013 *
Phenodex Cumulative (Final Model)	Parameter Estimates		p Value	Model Fitting
	Estimate	SE		Chi-square	p value
				16.2	0.001 *
Age	0.025	0.017	0.15
Serum fetuin-A	−0.11	0.088	0.23
T50	−0.010	0.004	0.016 *