Table 2.
The characteristics of patient derived PRP application.
PRP Preparation | |
Blood volume taken | 72 mL |
Anticoagulant | Sodium citrate 3.8% (w/v) |
System | Close |
Centrifugation | Once, 580 g/8 min |
Final PRP volume | 10 mL (IO) plus 8 mL (IA) |
PRP Characteristics | |
PRP Type | 13-00-11 |
MPV | 10.1 fL (CI: 9.30–10.50) |
Red Blood Cells | <0.01 × 106/μL |
White Blood Cells | <0.05 × 106/μL |
Activation | CaCl2 10% (w/v) |
Application Characteristics | |
Formulation type | Liquid |
Administration route | IO plus IA |
Dosage | 2 infiltrations at two weeks interval |
Volume | IO: 10 mL (5 mL acetabulum + 5 mL femoral head) IA injection: 8 mL |
Dose (range of platelets) | IO injection: 2.76 × 109–3.98 × 109 IA injection: 2.21 × 109–3.18 × 109 |
Tissue | Cartilage, synovium, subchondral bone |
Pathology | Hip osteoarthritis |
PRP: platelet-rich plasma; IA: intraarticular; IO: intraosseous; MPV: mean platelet volume.