Table 2. Pairwise age comparisons of first-positive RT-PCR viral load and estimated culture probability calculated from spline regression or raw data.
Only the spline-based regression adjusts for effects of the test center and RT-PCR system. Differences are mean differences, with 90% credible intervals or confidence intervals from null-hypothesis significance testing given in parentheses. P values are from Mann-Whitney U tests (96).
| Spline-based regression (adjusted) | Raw data (unadjusted) | ||||
| Sample | Comparison | Culture probability difference | log10(load difference) | log10(load difference) | P |
| All | 0–5 vs. 20–65 | –0.067 (–0.167, –0.002) | –0.50 (–0.62, –0.37) | –0.49 (–0.69, –0.29) | <0.001 |
| All | 5–10 vs. 20–65 | –0.054 (–0.132, –0.002) | –0.40 (–0.50, –0.30) | –0.38 (–0.64, –0.13) | 0.004 |
| All | 10–15 vs. 20–65 | –0.045 (–0.111, –0.002) | –0.30 (–0.39, –0.22) | –0.42 (–0.65, –0.18) | <0.001 |
| All | 15–20 vs. 20–65 | –0.033 (–0.076, –0.001) | –0.18 (–0.23, –0.12) | –0.16 (–0.31, –0.01) | 0.033 |
| PAMS | 0–5 vs. 20–65 | –0.067 (–0.167, –0.002) | –0.50 (–0.62, –0.37) | –0.49 (–0.69, –0.29) | <0.001 |
| PAMS | 5–10 vs. 20–65 | –0.112 (–0.279, –0.003) | –0.63 (–0.96, –0.32) | –0.37 (–1.00, 0.26) | 0.213 |
| PAMS | 10–15 vs. 20–65 | –0.092 (–0.228, –0.003) | –0.51 (–0.77, –0.26) | –0.86 (–1.46, –0.26) | 0.004 |
| PAMS | 15–20 vs. 20–65 | –0.064 (–0.162, –0.002) | –0.35 (–0.54, –0.17) | –0.56 (–1.10, –0.02) | 0.034 |
| Hospitalized | 0–5 vs. 20–65 | –0.033 (–0.087, –0.001) | –0.18 (–0.29, –0.07) | –0.26 (–0.52, –0.01) | 0.046 |
| Hospitalized | 5–10 vs. 20–65 | –0.028 (–0.104, 0.009) | –0.18 (–0.45, 0.07) | –0.36 (–1.10, 0.37) | 0.115 |
| Hospitalized | 10–15 vs. 20–65 | –0.025 (–0.084, 0.003) | –0.16 (–0.36, 0.03) | –0.48 (–1.38, 0.43) | 0.172 |
| Hospitalized | 15–20 vs. 20–65 | –0.022 (–0.071, 0.001) | –0.14 (–0.29, 0.02) | –0.11 (–0.97, 0.74) | 0.625 |
| Other | 0–5 vs. 20–65 | –0.018 (–0.055, 0.000) | –0.11 (–0.22, 0.01) | 0.00 (–0.33, 0.33) | 0.845 |
| Other | 5–10 vs. 20–65 | –0.058 (–0.148, –0.001) | –0.36 (–0.51, –0.20) | –0.33 (–0.55, –0.10) | 0.004 |
| Other | 10–15 vs. 20–65 | –0.044 (–0.110, –0.001) | –0.27 (–0.39, –0.15) | –0.10 (–0.40, 0.20) | 0.586 |
| Other | 15–20 vs. 20–65 | –0.026 (–0.072, –0.001) | –0.16 (–0.27, –0.06) | –0.31 (–0.58, –0.04) | 0.045 |