Table 1.
Baseline patient characteristics according to progression to severe disease *.
| Clinical Conditions | Total | Non-Severe Cases (n = 145/156) | Severe Cases * (n = 11/156) |
Fisher’s Exact Test p-Value |
|---|---|---|---|---|
| n | n (%) | n (%) | ||
| Sex | ||||
| Male | 102 | 93 (91.2) | 9 (8.8) | 0.332 |
| Female | 54 | 52 (96.3) | 2 (3.7) | |
| Age | ||||
| <60 years old | 108 | 100 (92.6) | 8 (7.4) | 1.000 |
| 60 and older | 48 | 45 (93.8) | 3 (6.3) | |
| Signs of pulmonary involvement | ||||
| O2 sat > 93% and CT ≤ 50% † | 124 | 121 (97.6) | 3 (2.4) | <0.001 |
| O2 sat ≤ 93% or CT > 50% | 32 | 24 (75.0) | 8 (25.0) | |
| Obesity | ||||
| No (BMI < 30 kg/m²) | 75 | 74 (98.7) | 1 (1.3) | 0.010 |
| Yes (BMI ≥ 30 kg/m²) | 81 | 71 (87.7) | 10 (12.3) | |
| Diabetes | ||||
| No | 116 | 115 (99.1) | 1 (0.9) | <0.001 |
| Yes | 40 | 30 (75.0) | 10 (25.0) | |
| Asthma/COPD | ||||
| No | 153 | 142 (92.8) | 11 (7.2) | 1.000 |
| Yes | 3 | 3 (100.0) | 0 (0.0) | |
| Dyslipidemia | ||||
| No | 131 | 122 (93.1) | 9 (6.9) | 0.690 |
| Yes | 25 | 23 (92.0) | 2 (8.0) | |
| Coronary artery disease | ||||
| No | 153 | 142 (92.8) | 11 (7.2) | 1.000 |
| Yes | 3 | 3 (100.0) | 0 (0.0) | |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; CT, computed tomography; O2 sat, oxygen saturation on room air. * Modified World Health Organization (WHO) Ordinal Scale for Clinical Improvement scores of 6–8. † Extent of lung involvement on initial chest CT scan estimated by visual assessment performed by a radiologist.