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. 2022 Jun 27;11(13):3713. doi: 10.3390/jcm11133713

Table 4.

Forward stepwise logistic regression model for the prediction of COVID-19 progression to severe disease.

Variables in the Equation β p-Value Odds Ratio
Step 1 Diabetes 3.64 0.001 38.0
Step 2 Diabetes 3.37 0.002 29.2
Lung involvement † 2.29 0.003 9.9
Step 3 Diabetes 3.74 0.001 42.0
Lung involvement 2.39 0.006 10.9
CD8+ NKG2A T cell MFI > 2054 2.78 0.020 16.0
Step 4
(Final model) *
Diabetes 3.71 0.002 40.9
Lung involvement 2.59 0.008 13.3
CD8+ NKG2A T cell MFI > 2054 2.65 0.037 14.2
Obesity 2.63 0.040 13.8

* Constant = −9.746; Hosmer–Lemeshow test, p = 0.948. † Significant lung involvement (oxygen saturation ≤93% or >50% lung involvement on computed tomography examination) on admission. MFI, mean fluorescent intensity; NKG2A, natural killer group 2 member A.