Table 3.

Multivariate logistic regression model for in-hospital mortality in very old (≥80 years) patients hospitalized with COVID-19 treated with remdesivir.

Independent Variables	Adjusted OR (95% CI)	p Value
Treatment with remdesivir	0.40 (0.24–0.66)	<0.001
Sociodemographic variables
Age	1.02 (0.99–1.00)	0.176
Sex, male	1.31 (1.00–1.79)	0.047
Acquisition
Community	1
Nosocomial	2.42 (1.43–4.09)	0.002
Nursing Home	1.46 (1.11–1.91)	0.006
Degree of dependence
Independent or mild	1
Moderate	2.01 (1.44–2.81)	<0.001
Severe	2.46 (1.66–3.67)	<0.001
Comorbidities
Baseline CCI	1.19 (1.11–1.27)	<0.001
Dementia	0.77 (0.54–1.08)	0.777
Symptoms and physical examination
Duration of symptoms in days	0.99 (0.98—1.00)	0.154
qSOFA index ≥2	3.39 (2.26–4.87)	<0.001
Chest X-ray findings
Normal	1
Unilateral infiltrates	1.03 (0.68–1.56)	0.887
Bilateral infiltrates	1.73 (1.21–2.48)	0.002
Laboratory findings
D-dimer	1.00 (1.00–1.00)	0.889
Other treatment
Systemic corticosteroids	1.65 (1.13–2.41)	0.009
Tocilizumab	1.42 (0.79–2.55)	0.234
Beta-lactams	1.43 (1.05–2.01)	0.022
Macrolides	0.91 (0.68–1.22)	0.551
High-flow nasal cannula oxygen	6.84 (3.79–12.34)	<0.001

CCI: Charlson Comorbidity Index; OR: odds ratio; CI: confidence interval; qSOFA: quick sequential organ failure assessment.