Table 2.

The optimal AUC of different indicators in T-SPOT results in differentiation between before and after successful treatment.

	Optimal AUC (95% CI)	Cutoff Value	Sensitivity % (95% CI)	Specificity % (95% CI)
ESAT-6	0.753 (0.687–0.819)	21.5	65.69 (55.63–74.81)	72.55 (62.82–80.92)
CFP-10	0.702 (0.630–0.774)	25.5	51.96 (41.84–61.96)	83.33 (74.66–89.98)
PHA	0.753 (0.687–0.820)	195.5	89.22 (81.52–94.49)	51.96 (41.84–61.96)
TBAg/PHA ratio	0.839 (0.785–0.894)	0.193	76.47 (67.04–84.31)	81.37 (72.45–88.40)

AUC, area under the curve; T-SPOT, T-SPOT.TB; ESAT-6, early secreted antigenic target 6; CFP-10, culture filtrate protein 10; PHA, phytohemagglutinin; TBAg/PHA, the ratio of TB-specific antigen to phytohemagglutinin.