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. 2022 Jul 2;11(13):3844. doi: 10.3390/jcm11133844

Figure 2.

Figure 2

The relation between SARS-CoV-2 infection and coagulation complications. Infection with SARS-CoV-2 stimulates the innate immune system by releasing proinflammatory cytokines. Interleukin (Il)-6, tumour necrosis factor (TNF)-α, interferon (IFN)-γ and C-reactive protein (CRP) interfere with the anticoagulant pathway and inhibit fibrinolysis. Due to all these mechanisms, coagulation is stimulated and ends with fibrin development.