Table 2.
Characteristics of patients, nuclear dosimetric data, fetal FDG-avid structures and outcomes.
| Patient | Imaging Method | Gestational Age (Weeks) | Weight (kg) | Administered Activity-Injected Dose (MBq) | CT Absorbed Dose (mGy) | PET Absorbed Dose (mGy) | Total Absorbed Dose (mGy) | Fraction | Time Integrated Activity (Bq-h/Bq) | Fetal FDG-Avid Structures | Fetal Negative Outcomes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PET/CT | 26 | / | 188 | ~0 | 3.2 | 3.2 | / | / | Head and body | ND |
| 2 | PET/CT | 22 | / | 355 | 6 | 6.4 | 12.4 | / | / | Whole fetus | ND |
| 3 | PET/CT | 8 | 60 | 320 | 8.3 | 10.6 | 18.9 | 0.0020 | 0.0053 | Whole fetus | No |
| 4 | PET/CT | 10 | 71 | 296 | 10 | 11.8 | 21.8 | 0.0018 | 0.0046 | Whole fetus | NA (Therapeutic interruption) |
| 5 | PET/CT | 6 | 67.6 | 583 | ~0 | 9.04 | 9.04 | 0 | 0 | Whole fetus | No |
| 6 | PET/CT | 18 | 87.8 | 200 | ~0 | 1.43 | 1.43 | 0.00086 | 0.0023 | Whole fetus Myocardium | No |
| 7 | PET/CT | 25 | 67.1 | 337 | ~0 | 2.1 | 2.1 | 0.0084 | 0.0223 | Whole fetus Myocardium | No |
| 8 | PET/CT | 28 | 81.8 | 174 | ~0 | 1.01 | 1.01 | 0.0071 | 0.0187 | Whole fetus Myocardium |
No |
| 9 | PET/CT | 30 | 88.6 | 229 | ~0 | 2.43 | 2.43 | 0.0196 | 0.0518 | Myocardium | No |
| 10 | PET/CT | 23 | 58.9 | 181 | ~0 | 1.1 | 1.1 | 0.0078 | 0.0206 | Whole fetus Myocardium |
No |
| 11 | PET/CT | 21 | 53 | 181 | 3.6 | 5 | 8.6 | 0.0049 | 0.0129 | Whole fetus, Brain | No |
| 12 | PET/CT | 26 | / | 370 | 3.6 | 6.29 | 9.89 | / | / | Myocardium Kidneys | ND |
| 13 | PET/CT | 26 | / | ND | 3.2 | 4.1 | 7.3 | / | / | Myocardium | No |
| 14 | PET/CT | 34 | 95 | 555 | / | / | / | 0.0192 | 0.0507 | ND | ND |
| 15 | PET/CT | 5 | 85.8 | 296 | ND | 5.1 | NA | 0.00115 | 0.003 | Myocardium Kidneys Bladder |
ND |
| 16 | PET/CT | 12 | 58.1 | 385 | ND | 2.8 | NA | 0.00061 | 0.0016 | ND | |
| 17 | PET | ~12 | 77.1 | 350 | ~0 | 2.7 | 2.7 | 0.001 | 0.0026 | ND | |
| 18 | PET/MR | 19 | 69.9 | 296 | NA | 1.4 | 1.4 | 0.00366 | 0.0097 | ND | |
| 19 | PET/MR | 19 | 50.8 | 348 | NA | 1.4 | 1.4 | 0.00238 | 0.0063 | ND | |
| 20 | PET | 28 | 65.8 | 296 | ~0 | 1.8 | 1.8 | 0.01951 | 0.0515 | ND | |
| 21 (twins) |
PET/CT | 25 | 76 | 188 | / | / | / | 0.0156 | 0.0412 | ND | ND |
| PET/CT | 25 | 76 | 188 | / | / | / | 0.0164 | 0.0434 | ND | ND | |
| 22 | PET/TC | 28 | / | 173 | 3.1 | 2.8 | 5.9 | / | / | Myocardiu Kidneys, Bladder Head |
No |
| 23 | PET/TC | 30 | / | ND | / | / | 1.9 | / | / | Myocardium | No |
| 24 | PET/CT | 31 | / | 146 | 3.9 | / | 1.7 | 0.052 | 0.137 | ND | No |
Abbreviations: PET, positron emission tomography; CT, computed tomography; MR, magnetic resonance; FDG, 18-F-fluorodesossyglucose; ND, not described.