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H. erinaceus mycelium inhibits IL-1β and TNF-α expression in synovial tissue. (A,C) Representative images of IL-1β and TNF-α staining. (B,D) Quantification of IHC scores (n = 6 for each group). * p < 0.05 compared to the control group; # p < 0.05 compared to the ACLT-only group.
