Table 2.
Frequency of the main symptoms before and after diagnosis celiac disease.
| Symptoms before Diagnosis | Symptoms after the Implementation of a Gluten-Free | |||||
|---|---|---|---|---|---|---|
| Adults n (%) | Children n (%) | Adults n (%) | p-Value | Children n (%) | p-Value | |
| Abdominal pain and bloating | 62 (96.8) | 16 (69.5) | 16 (25.0) | <0.05 | 7 (30.4) | <0.05 |
| Diarrhea and steatorrhea | 53 (82.8) | 11 (47.8) | 9 (14.1) | <0.05 | 4 (17.4) | <0.05 |
| Constipation | 5 (7.8) | 6 (26.1) | 1 (1.6) | <0.05 | 3 (13.1) | <0.05 |
| Weight loss | 7 (10.9) | 7 (30.4) | 1 (1.6) | <0.05 | 0 | <0.05 |
| Low height | 9 (14.1) | 15 (65.2) | 9 (14.1) | ns | 6 (26.1) | <0.05 |
| Aphthous mouth ulcers | 37 (57.8) | 14 (60.8) | 7 (10.9) | <0.05 | 10 (43.5) | <0.05 |
| Enamel hypoplasia | 6 (9.3) | 11 (47.8) | 6 (9.3) | ns | 11 (47.8) | ns |
| Chronic fatigue | 37 (57.8) | 12 (52.2) | 6 (9.3) | <0.05 | 1 (4.3) | <0.05 |
| Concentration problems | 39 (60.9) | 19 (82.6) | 4 (6.3) | <0.05 | 6 (26.1) | <0.05 |
| Neurological disorders (peripheral neuropathy, ataxia, epilepsy) | 6 (9.3) | 3 (13.0) | 6 (9.3) | ns | 3 (13.1) | ns |
| Chronic headache, migraine | 28 (43.7) | 9 (39.1) | 13 (20.3) | <0.05 | 3 (13.1) | <0.05 |
| Joint pain | 21 (32.8) | 7 (30.4) | 5 (7.8) | <0.05 | 2 (8.6) | <0.05 |
| Brain fog | 14 (21.8) | 5 (21.7) | 8 (12.5) | <0.05 | 2 (8.6) | <0.05 |
| Dermatological issues (Duhring’s disease) | 26 (40.6) | 7 (30.4) | 3 (4.7) | <0.05 | 5 (21.7) | <0.05 |
| Fertility problems | 12 (18.8) | 0 | 9 (14.1) | <0.05 | 0 | ns |
| Malabsorption of vitamin B12 | 13 (20.3) | 4 (17.4) | 5 (7.8) | <0.05 | 1 (4.3) | <0.05 |
| Chronic anemia | 20 (31.2) | 9 (39.1) | 6 (9.3) | <0.05 | 5 (21.7) | <0.05 |
| Other | 14 (21.8) | 7 (30.4) | 4 (6.3) | <0.05 | 2 (8.6) | <0.05 |