Table 1.
Baseline (1996–1997) characteristics by inclusion statusa
| Baseline Characteristics | Analytic sample N=1551 |
Excluded N=1751 |
p-value |
|---|---|---|---|
| CES-D≥16, n (%) | 354 (22.82) | 450 (25.77) | 0.05 |
| CES-D score, mean±SD | 10.14±10.07 | 11.25±9.32 | 0.001 |
| Age (years), mean±SD | 45.79±2.68 | 45.91±2.70 | 0.20 |
| Race/Ethnicity, n (%) | <.0001 | ||
| White | 667 (43.00) | 884 (50.49) | |
| Black | 457 (29.46) | 477 (27.24) | |
| Chinese | 147 (9.48) | 103 (5.88) | |
| Hispanic | 108 (6.96) | 178 (10.17) | |
| Japanese | 172 (11.09) | 109 (6.23) | |
| Education, n (%) | 0.16 | ||
| Less than High school | 123 (8.00) | 115 (6.63) | |
| High school/Some college | 745 (48.47) | 887 (51.15) | |
| College/More than college | 669 (43.53) | 732 (42.21) | |
| Body Mass Index (kg/m2), mean±SD | 28.21±7.38 | 28.32±7.06 | 0.66 |
| Financial Strainb, n (%) | 617 (40.06) | 695 (39.94) | 0.94 |
| Medication for nervous conditionc, n (%) | 114 (7.37) | 214 (12.27) | <.0001 |
| Poor role emotional score, n (%) | 496 (32.04) | 626 (35.81) | 0.02 |
| Poor role physical score, n (%) | 393 (25.39) | 543 (31.05) | 0.0003 |
| Poor social function score, n (%) | 376 (24.26) | 518 (29.63) | 0.0005 |
| Anxiety symptom score≥4, n (%) | 309 (20.13) | 434 (25.16) | 0.0006 |
| Social support, mean±SD | 12.29±3.34 | 12.34±3.37 | 0.67 |
| Stressful life events, n (%) | 0.003 | ||
| 0 | 821 (53.17) | 823 (47.30) | |
| 1 | 307 (19.88) | 372 (21.38) | |
| 2+ | 416 (26.94) | 545 (31.32) | |
| Number of comorbiditiesd, n (%) | 0.03 | ||
| 0 | 802 (53.04) | 834 (48.49) | |
| 1 | 453 (29.96) | 556 (32.33) | |
| 2+ | 257 (17.00) | 330 (19.19) | |
| Sleep problems, n (%) | 436 (28.29) | 587 (33.64) | 0.001 |
| Vasomotor symptoms, n (%) | 545 (35.32) | 745 (42.79) | <.0001 |
| Menopause status, n (%) | 0.0001 | ||
| Early perimenopause | 662 (42.88) | 839 (48.41) | |
| Pre-menopause | 882 (57.12) | 888 (51.24) | |
| Symptom Sensitivity, mean±SD | 10.10±3.54 | 10.29±3.66 | 0.18 |
| C-reactive protein, median (Q1–Q3)e | 1.73(0.53–5.66) | 1.98(0.64–5.93) | 0.23 |
a
To be included in the analytic sample women had to have a baseline measure of the CES-D (Center for Epidemiologic Studies-Depression) scale, at least one follow-up CES-D measure and an observed FMP (final menstrual period). SD, standard deviation. Significant p-values in bold font.
b
Financial strain: very or somewhat difficult paying for basics (n, % shown) versus not difficult at all.
c
Medication for nervous conditions includes antidepressants, tranquilizers, sedatives, and sleeping pills.
d
Comorbidities included diabetes, hypertension, arthritis/osteoarthritis, under/overactive thyroid, osteoporosis, high cholesterol, heart attack, angina, stroke, or cancer.
e
Q1–Q3, interquartile range.