Table 2.
Adjusted Association of Pre-FMP CES-D Trajectories with High Depressive Symptoms (CES-D≥16) during the Post-FMP (Postmenopause) (N=1,551, Number of observations=5,232)
| Modela | CES-D≥16 during Postmenopause OR (95% CI) | p-value |
|---|---|---|
| Pre-FMP CES-D trajectory group | ||
| Consistently low CES-D scores (REF) | --- | --- |
| Mid-level CES-D scores | 2.62 (1.89–3.66) | <.0001 |
| High CES-D scores | 6.88 (4.72–10.02) | <.0001 |
FMP, Final Menstrual Period; CES-D, Center for Epidemiologic Studies-Depression scale; OR, Odds Ratio; CI, Confidence Interval; REF, referent group.
a
Adjusted for site, time, age at baseline, race/ethnicity, education at baseline, stressful life events, medications for nervous conditions, social support, poor role emotional score, poor social function score, significant anxiety symptoms, and sleep problems. Covariates are time-varying from the FMP forward unless described as baseline variables