Table 2.

ADMET properties of the selected compounds for MSTN protein.

S. No.	Molecule	BBB Permeant	PAINS	WLOGP	TPSA	Log S	Skin Permeability	CYP2D6 Inhibitor	Carcinogenicity
1.	ZINC85542795	No	0	8.79	72.72	−12.48	−2.98	No	None
2.	ZINC85531289	No	0	7.4	121.5	−10.37	−5.04	No	None
3.	ZINC85542877	No	0	8.63	72.72	−12.42	−2.95	No	None
4.	ZINC85542671	No	0	7.73	84.75	−10.87	−4.17	No	None
5.	ZINC85541288	No	0	5.5	61.42	−6.92	−5.57	No	None
6.	ZINC85532197	No	0	8.31	127.62	−10.4	−5.24	No	None
7.	ZINC85511481	No	0	5.91	173.98	−9.86	−6.08	No	None
8.	ZINC85592908	No	0	7.13	117.84	−9.54	−5.21	No	None
9.	ZINC14680812	No	0	3.69	158.68	−4.19	−8.53	No	None
10.	ZINC85592903	No	0	6.14	117.84	−8.63	−5.67	No	None
11.	ZINC85531359	No	0	4.29	141.73	−6.83	−7.14	No	None
12.	ZINC70454202	No	0	4.59	92.21	−8.13	−5.38	No	None
13.	ZINC95910145	No	0	5.2	72.42	−6.82	−5.71	No	None
14.	ZINC44086846	No	0	5.68	72.75	−6.74	−5.76	No	None
15.	ZINC04098631	No	0	6.27	79.15	−7.88	−4.43	No	None
16.	ZINC85991498	No	0	5.39	109.94	−6.7	−6.34	No	None
17.	Curcumin	No	0	3.15	93.06	−4.83	−6.28	No	None

BB (Blood–brain barrier) penetration ability, GIA (Gastrointestinal absorption), PSA (Polar surface area): ≤90Å2 is the optimum value, LogS: water solubility.