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. 2022 Jul 5;27(13):4321. doi: 10.3390/molecules27134321

Table 3.

Percent inhibition of acetylcholinesterase by MEC and NBFC.

Compound/Plant Extract/Fraction Concentration (µg/mL) % AChE Inhibition IC50
(µg/mL)
Galantamine Standard 1000 95.67 ± 2.52 5.0
500 87.33 ± 2.52
250 82.67 ± 3.06
125 77.00 ± 3.00
Chrozophora
tinctoria
MEC 1000 83.33 ± 3.51 40
500 73.00 ± 3.00
250 68.33 ± 4.51
125 61.00 ± 2.00
NBFC 1000 73.33 ± 3.06 110
500 65.00 ± 2.65
250 57.67 ± 2.08
125 50.33 ± 2.52

Values are expressed as mean ± SEM. Statistical significance was determined using IC50 values through Biostata software. IC50 = half-maximal inhibitory concentration; MEC= methanolic extract of C. tinctoria; AChE = Acetylcholinesterase; NBFC = n-butanol fraction of Chrozophora tinctoria.