Table 5.
Results of analgesic activity following hot plate model.
| Samples | Dose mg/kg | Reaction Time on Hot Plate in (min) | |||
|---|---|---|---|---|---|
| 15 | 30 | 45 | 60 | ||
| -ve control | - | 3.91 ± 0.52 | 4.95 ± 0.39 | 3.35 ± 0.59 | 1.73 ± 0.44 |
| FM10 | 25 | 8.50 ± 0.64 *** | 8.83 ± 0.64 *** | 7.52 ± 0.76 *** | 6.66 ± 0.33 *** |
| 50 | 10.78 ± 0.32 *** | 9.26 ± 0.43 *** | 9.10 ± 0.57 *** | 8.74 ± 0.46 *** | |
| 75 | 13.52 ± 0.65 *** | 12.23 ± 0.44 *** | 11.54 ± 0.64 *** | 10.36 ± 0.54 *** | |
| FM12 | 25 | 7.50 ± 0.64 *** | 8.36 ± 0.49 *** | 7.27 ± 0.48 *** | 6.45 ± 0.74 *** |
| 50 | 9.42 ± 0.74 *** | 8.52 ± 0.45 *** | 8.26 ± 0.47 *** | 7.39 ± 0.67 *** | |
| 75 | 12.44 ± 0.62 *** | 11.51 ± 0.62 *** | 9.54 ± 0.75 *** | 9.36 ± 0.54 *** | |
| Morphine | 5 | 12.88 ± 0.26 *** | 12.31 ± 0.62 *** | 11.86 ± 0.87 *** | 11.22 ± 0.45 *** |
The values are existing as the mean ± SEM (n = 5). The asterisks display significance level in comparison with negative control: data were analyzed via Dunnett’s test; *** p < 0.001.