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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
S1, S2, and S3 represent the three predicted potential binding sites by blind docking of scoulerine (blue) to α (green) and β (red) tubulins of 1SA0 PDB structure. Colchicine derivative from 1SA0 in S1 and laulimalide from 404H in S2 are shown in white.