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. 2022 Jun 23;14(13):2600. doi: 10.3390/nu14132600

Figure 3.

Figure 3

Increased extracellular [Na+] increased [Ca2+]i in single AgRP neurons from TRPV1 KO mice. (A,B) Typical example of [Ca2+]i responses to [Na+] increase and 10−5 M glutamate (GA) in AgRP neurons from wild-type mice (A) and TRPV1 KO mice (B). Scale bar is 20 μm. (C) Average amplitude of [Ca2+]i responses to increased extracellular [Na+] (Δratio) in AgRP neurons. Data are presented as mean ± SEM. WT vs. KO determined by one-way ANOVA followed by the Bonferroni test.