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Glucose increased [Ca2+]i in single POMC neurons. (A,B) Glucose (8.3 mM) increased [Ca2+]i in POMC neurons from wild-type (WT) mice (A) and TRPV1 KO mice (B). Scale bar is 20 μm. (C) Average amplitude of [Ca2+]i responses (Δratio) in POMC neurons. Data are presented as mean ± SEM. WT vs. KO determined by one-way ANOVA followed by the Bonferroni test.
