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. 2022 Jun 30;27(13):4227. doi: 10.3390/molecules27134227

Figure 5.

Figure 5

Effects of naringenin and 8-PN on insulin-signaling defect in skeletal muscle and hepatic apoptosis. (A) Representative Western blot images of phospho-PI3K, PI3K, phospho-AKT, AKT, phospho-p65, and p65 in the skeletal muscle and (B) corresponding quantitative data. (C) Representative Western blot images of Bcl2, Bax, cleaved PARP, cleaved caspase-3, cleaved caspase-9, and cleaved caspase-8 in the liver and (D) corresponding quantitative data. V, vehicle; NAR, naringenin; 8-PN, 8-prenylnaringenin. Data are shown as means ± SEM (n = 6). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. STZ vehicle group.