Table 2.

(A). Kinetic models for loading of aprepitant into the fabricated IONPs@SiO₂-PA@B composite materials. (B). Kinetic models for the loading of sofosbuvir into the IONPs@SiO₂-PA@B composite materials.

(A)
	IONPs@SiO21:PA@B1	IONPs@SiO21: PA@B3	IONPs@SiO21: PA@B5	IONPs@SiO23: PA@B5	IONPs@SiO25: PA@B5
qe (exp) mg/g	193.82	193.903	194.02	194.02	194.06
Pseudo-first-order kinetic model
K1(min−1)	−0.035	−0.18	−0.042	−0.015	−0.042
qe (mg/g)	8.18	9.79	9.86	4.56	9.98
R2	0.92	0.91	0.91	0.92	0.91
Pseudo-second-order kinetic model
K2(min−1)	0.001	0.001	0.001	0.001	0.001
qe (mg/g)	197.08	197.08	197.08	197.08	197.08
R2	1	1	1	1	1
Intra-particle diffusion model
Kint	0.336	0.338	0.342	0.342	0.345
C	189.18	189.25	189.33	189.34	189.32
R2	0.901	0.898	0.897	0.893	0.898
(B)
	IONPs@SiO21:PA@B1	IONPs@SiO21:PA@B3	IONPs@SiO21:PA@B5	IONPs@SiO23:PA@B5	IONPs@SiO25:PA@B5
qe (exp) mg/g	194.29	194.43	194.53	194.57	194.57
Pseudo-first-order kinetic model
K1(min−1)	−0.027	−0.026	−0.025	−0.027	−0.029
qe (mg/g)	7.05	6.92	6.73	7.24	7.57
R2	0.93	0.94	0.94	0.93	0.93
Pseudo-second-order kinetic model
K2(min−1)	0.001	0.001	0.001	0.001	0.001
qe (mg/g)	196.07	196.07	196.07	196.07	196.07
R2	1	1	1	1	1
Intra-particle diffusion model
Kint	0.366	0.366	0.366	0.366	0.370
C	187.37	187.37	189.37	189.41	189.42
R2	0.895	0.899	0.902	0.898	0.893