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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Pediatr Obes. 2021 Dec 16;17(5):e12876. doi: 10.1111/ijpo.12876

Table 5. Daily Infant Intakes of Human Milk Amino Acids are Associated with Infant Body Composition at 0.5 - 6 Months of Age.

Linear mixed-effects models included infant weight-for-length z-score (WLZ), fat mass index (FMI), and fat free mass index (FFMI) over the first 6 months of life (time points 0.5, 2, and 6 months) as the dependent variables and infants' intakes of human milk amino acids (μmol/day) as the fixed effects. Model covariates included: infant age, infant birth weight, infant sex (FMI and FFMI models only), maternal BMI, gestational weight gain, maternal race, delivery mode (vaginal or C-section), and breastfeeding status. Random effects included: participant identification number, to account for repeated measures. Asp = aspartic acid, C-C = cystine, Gln = glutamine, Glu = glutamic acid, His = histidine, and Ser = serine.

Weight-for-Length
Z-score
Fat Mass Index
(kg fat mass / m2)
Fat Free Mass Index
(kg fat free mass / m2)
Amino Acid Intake
(μmol/day)
β p-value β p-value β p-value
Asp 0.0024 0.093 0.0038 0.011 0.0034 0.011
C-C 0.0103 0.088 0.0174 0.006 0.0163 0.004
Gln 0.0004 0.15 0.0011 <0.001 0.0007 0.009
Glu 0.0004 0.042 0.0005 0.005 0.0004 0.026
His 0.0080 0.039 0.0106 0.008 0.0088 0.015
Ser 0.0011 0.23 0.0029 0.002 0.0014 0.088