Table 3.
Compound | IC50 (μM) a | |
---|---|---|
A2780 | IOSE80PC | |
8 | 9.99 ± 0.98 | >100 |
10 | 25.63 ± 1.80 | >100 |
11 | 48.67 ± 0.31 | >100 |
12 | 57.45 ± 3.08 | >100 |
14 | 71.24 ± 11.29 | >100 |
16 | 48.54 ± 1.97 | >100 |
17 | 23.72 ± 2.54 | >100 |
21 | 7.36 ± 0.58 | 65.84 ± 1.60 |
Cisplatin | 10.73 ± 0.81 | 12.78 ± 0.55 |
Quercetin | 19.45 ± 2.92 | >100 |
a IC50 value is defined as the concentration that reduces cell number by 50% compared to control cultures. Compounds 1–7, 9, 13, 15, 18–20, and 22 were not active (IC50 > 100 μM) in A2780 cells. The inactive compounds were not tested on IOSE80PC.