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. 2022 Jun 22;11(13):1651. doi: 10.3390/plants11131651

Table 3.

The cytotoxicity of compounds 122 isolated from Pueraria Flos against human ovarian cell lines A2780 and IOSE80PC.

Compound IC50 (μM) a
A2780 IOSE80PC
8 9.99 ± 0.98 >100
10 25.63 ± 1.80 >100
11 48.67 ± 0.31 >100
12 57.45 ± 3.08 >100
14 71.24 ± 11.29 >100
16 48.54 ± 1.97 >100
17 23.72 ± 2.54 >100
21 7.36 ± 0.58 65.84 ± 1.60
Cisplatin 10.73 ± 0.81 12.78 ± 0.55
Quercetin 19.45 ± 2.92 >100

a IC50 value is defined as the concentration that reduces cell number by 50% compared to control cultures. Compounds 17, 9, 13, 15, 1820, and 22 were not active (IC50 > 100 μM) in A2780 cells. The inactive compounds were not tested on IOSE80PC.