Table 7.

Fracture strength/Fracture Resistance/Fracture Load/Failure Load Results.

Author and Year	Exposure Agent/Aging Technique	Testing Machine Used	Mean Maximum Force at Fracture for Conventional Resin (N)	Mean Maximum Force at Fracture for CAD/CAM Milled Resin (N)	Mean Maximum Force at Fracture for 3D-Printed Resin (N)	Conclusions and/or Suggestions
Reeponmaha et al., 2020 [16]	(A) Thermal Cycling: 5000 cycles at 5–55 °C (B) Cyclic occlusal load: 100 N at 4 Hz for 100,000 cycles	Universal testing machine	(A) Unifast Trad: 657.87 ± 82.84 (B) Protemp 4: 1125.94 ± 168.07	(C) Brylic Solid: 953.60 ± 58.88	(D) Freeprint Temp: 1004.19 ± 122.18	FS: Conventionally fabricated bis-acryl > 3D-printed MMA > CAD/CAM-milled PMMA > conventionally fabricated methylmethacrylate. No significant difference of fracture strength between conventionally fabricated Bis-acryl, 3D-printed MMA, and CAD/CAM-milled PMMA.
Ibrahim et al., 2020 [38]	(A) Thermocycling: 1250 cycles at 5–55 °C (B) Mechanical aging: 50 N, 37,500 cycles	Universal testing machine	N/A	(A) TelioCAD: 933.46 ± 104.49	(B) Next dent C&B resin: 1226.48 ± 48.33	FR: 3D-printed PMMA > CAD/CAM milled MMA (significantly high)
Suralik et al., 2020 [39]	N/M	Universal Instron machine	(A) Jet:300.61 ± 98.94	(B) Zirlux Temp: 294.64 ± 60.34	(C) Freeprint Temp: 408.49 ± 132.16	Fracture strength: 3D-printed Methacrylate-based resin > CAD/CAM-milled PMMA> conventionally fabricated PMMA FS of 3D-printed resin is significantly greater.
Reymus et al., 2020 [40]	Artificial aging: stored in distilled water for 21 days at 37 °C in an incubator.	Universal testing machine	(A) Luxatemp: 551.7 ± 130	(B) Telio CAD: 881.4 ± 239.2	Depending on type of post-curing unit used: [Otoflash (OF), Printbox (PB), Labolight (LL)] (C) Experimental: LL: 585.4 ± 66.8, OF: 746.4 ± 62.1, PB: 874.3 ± 104.0 (D) NextDent C&B LL: 775.9 ± 57.6, OF: 1050.4 ± 133.3, PB: 871.5 ± 398.1 (E) Freeprint temp LL: 777.6 ± 95.9, OF: 638.0 ± 175.5, PB: 598.6 ± 170.1 (F) 3Delta temp LL: 609.6 ± 118.8, OF: 868.2 ± 139.8, PB: 678.4 ± 193.7	FL: 3D-Printed MMA > or < CAD/CAM milled MMA (based on post-curing unit use(D) > Conventional Bis-acrylic
Mayer et al., 2020 [50]	Three different cleaning methods for 3D printed specimens and chewing simulation (vertical load of 50 N and a lateral movement of 0.7 mm for 480,000 masticatory cycles)	Universal testing machine	N/A	(A) Telio CAD: 1427 ± 77	(B) Freeprint temp: 623 ± 156, 539 ± 152 & 615 ± 124 ((C) GC Temp PRINT: 878 ± 139, 796 ± 121, 831 ± 260 ((D) Next dent C&B MFH: 750 ± 156, 660 ± 198, 813 ± 157	FL: CAD/CAM Milled PMMA > 3D-Printed (MMA & UDM(A) FL amongst 3D-Printed: GC Temp PRINT > Next dent C&B MFH > Freeprint temp
Abad-Coronel et al., 2021 [46]	Thermocycling: 5000 cycles, at 5 °C and 55 °C in distilled water	Universal testing machine	N/A	(A) Vipiblock Trilux: 1663.57 ± 130.25	PriZma 3D Bio Prov: 1437.74 ± 73.41	FS: CAD/CAM Milled PMMA > 3D-Printed micro-hybrid resins
Martín-Ortega et al., 2022 [52]	Thermocycling: 525,000 cycles, at 5 °C to 55 °C	Universal testing machine	N/A	(A) and (C): Vivodent CAD Multi: Anterior group: 988.4 ± 54.8 Posterior group: 423.8 ± 68.0	(B) and (D): SHERAprint-cb: Anterior group: 636.5 ± 277.1 Posterior group: 321.3 ± 128.6 N	FR: CAD/CAM Milled PMMA > 3D-Printed photopolymer resinFR: Anterior group > Posterior group
Henderson et al., 2022 [51]	Storage time in incubator (1 day or 30 days).	Universal testing machine	3M-Paradigm: Loading Rate -Combined 1 and 10 mm/min Storage time: 1 day: 537 ± 117 N 30 Days: 572 ± 139 N	Solid Shade PMMA Disc: Loading Rate -Combined 1 and 10 mm/Min Storage time: 1 day: 683 ± 115 N 30 Days: 547 ± 92 N	Dentca Crown and Bridge resin: Loading Rate—Combined 1 and 10 mm/Min Storage time: 1 day: 522 ± 98 N 30 Days: 416 ± 109 N	FaL: CAD/CAM Milled > Conventional > 3D-Printed

N: Newton; N/A: Not Applicable; N/M: Not Mentioned; FS: Fracture Strength; FR: Fracture resistance; FL: Fracture load; FaL: Failure Load.