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Actions of tetrahydrocannabinol and cannabidiol
| Tetrahydrocannabinol | Cannabidiol |
|---|---|
| Partial agonist at CB1 and CB2 | Noncompetitive antagonist at CB1, inverse agonist at CB2 |
| Analgesic | Anticonvulsant |
| Muscle relaxation | Anti-inflammatory |
| Antiemetic | Anxiolytic |
| Appetite stimulation | Analgesia |
| Psychoactive | Neuroprotective |
| May inhibit psychoactive effects of THC |
Adapted from Davison & Davison, 2011 (22). CB, cannabinoid receptor.
