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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Int J Obes (Lond). 2021 Nov 9;46(3):494–501. doi: 10.1038/s41366-021-01003-0

Table 4.

Associations of exposure to PM2.5 and O3 at the residential address during pregnancy with indicators of adiposity at age 4–6 years - model 3.

Exposure (increment) Overweight Waist circumference Percent fat mass FMI
OR (95% CI) β (95% CI) β (95% CI) β (95% CI)
Trimester 1 average PM2.5 (1.3 μg/m3) 0.95 (0.69, 1.30) −0.08 (−0.48, 0.32) −0.28 (−0.94, 0.38) −0.06 (−0.18, 0.06)
Trimester 2 average PM2.5 (1.3 μg/m3) 1.06 (0.78, 1.43) 0.32 (−0.07, 0.72) 0.70 (0.05, 1.35) 0.13 (0.01, 0.25)
Trimester 3 average PM2.5 (1.3 μg/m3) 1.03 (0.74, 1.43) −0.25 (−0.66, 0.16) 1.17 (1.84,0.50) 0.18 (0.31,0.06)
Full pregnancy average PM2.5 (0.9 μg/m3) 1.10 (0.77, 1.57) −0.05 (−0.51, 0.40) −0.35 (−1.12, 0.42) −0.05 (−0.19, 0.09)
Trimester 1 average 8-hr max O3 (20.4 ppb) 0.95 (0.37, 2.43) −0.14 (−1.27, 1.00) 2.49 (4.39,0.58) −0.35 (−0.70, 0.01)
Trimester 2 average 8-hr max O3 (18.0 ppb) 1.19 (0.54, 2.62) −0.04 (−1.03, 0.96) 0.04 (−1.59, 1.67) 0.03 (−0.28, 0.33)
Trimester 3 average 8-hr max O3 (18.7 ppb) 1.12 (0.50, 2.51) −0.98 (−2.03, 0.07) 1.89 (0.15, 3.63) 0.25 (−0.08, 0.57)
Full pregnancy average 8-hr max O3 (5.8 ppb) 1.32 (0.79, 2.20) −0.37 (−1.01, 0.27) −0.45 (−1.54, 0.64) −0.06 (−0.26, 0.14)

Abbreviations: PM2.5 = fine particulate matter; O3 = ozone; FMI = fat mass index. Statistically significant results are highlighted in bold (p <0.05).

Associations are shown for an interquartile range increase in exposure. Associations are adjusted for child’s sex, child’s age, maternal age at delivery, pre-pregnancy BMI, parity, race/ethnicity, maternal level of education, maternal smoking during pregnancy, season of birth and median income in the Census tract. Associations with PM2.5 are additionally adjusted for the average 8-hour maximum O3 concentration during the specified pregnancy period. Associations with O3 are additionally adjusted for the average daily PM2.5 concentration during the specified pregnancy period.