TABLE 4.

Correlation of UPDRS III scores and ddPCR relative expression

		UPDRS, Total	UPDRS, Change	LRRK2	HMOX1	TLR2	TLR8	RELA	ATG7	GABARAPL2
UPDRS, Total	r	1.0000	0.6867	0.3299	.1598	.3665	−0.0089	−0.1380	−0.5960	−0.0115
	p		1.4E‐09	0.0100	0.2226	0.0040	0.9462	0.2931	5.1E‐07	0.9305
UPDRS, Change	r	0.6867	1.0000	0.2469	0.3193	0.4388	0.0385	−0.1464	−0.5662	−0.0360
	p	1.4E‐09		0.0572	0.0129	.0005	0.7702	0.2643	2.4E‐06	0.7847
LRRK2	r	0.3299	.2469	1.0000	0.4972	0.2741	0.4069	−0.0481	−0.5733	−.1201
	p	0.0100	0.0572		0.0001	0.0341	0.0013	0.7152	1.7E‐06	0.3608
HMOX1	r	0.1598	0.3193	0.4972	1.0000	0.2171	0.2956	0.0207	−0.2649	−0.1893
	p	0.2226	0.0129	0.0001		0.0956	0.0218	0.8750	0.0408	0.1475
TLR2	r	0.3665	.4388	0.2741	0.2171	1.0000	0.4184	0.1560	−0.6452	−0.0876
	p	0.0040	0.0005	0.0341	0.0956		0.0009	0.2340	2.6E‐08	0.5057
TLR8	r	−0.0089	0.0385	0.4069	0.2956	0.4184	1.0000	0.1341	−0.3704	0.1620
	p	0.9462	0.7702	0.0013	0.0218	0.0009		0.3069	0.0036	0.2162
RELA	r	−0.1380	−0.1464	−0.0481	0.0207	0.1560	0.1341	1.0000	0.0132	0.2511
	p	0.2931	0.2643	0.7152	0.8750	0.2340	0.3069		0.9204	0.0530
ATG7	r	−0.5960	−0.5662	−0.5733	−0.2649	−0.6452	−0.3704	0.0132	1.0000	0.0417
	p	5.1E‐07	2.4E‐06	1.7E‐06	0.0408	2.6E‐08	0.0036	0.9204		0.7519
GABARAPL2	r	−0.0115	−0.0360	−0.1201	−0.1893	−0.0876	0.1620	0.2511	0.0417	1.0000
	p	0.9305	0.7847	0.3608	0.1475	0.5057	0.2162	0.0530	0.7519

r, Pearson product moment correlation coefficient; p, p value.