Table 2. Summary of several cases of ITP after natural COVID-19 infection, illustrating possible presentation, disease course, and interventions made by various authors.

IVIG: intravenous immunoglobulin; COVID-19: coronavirus disease 2019; ITP: immune thrombocytopenic purpura; Y: year

S. no.	Case	Patient demographics	Presentation	Platelet level trend (per microliter)	Intervention	Vaccination
1	Zulfiqar et al. (2020) [12]	65Y female	4 days of fever, fatigue, dry cough, abdominal discomfort. Covid 19 positive	183,000 >16,000 > 8000 >on treatment >10,000 > 139,000	Platelet transfusion, prednisolone 100mg, eltrombopag 75mg/day	Not reported
2	Malik et al. (2020) [13]	29Y female	Malaise, body ache. COVID-19-positive	20,000 > 18,000 > 7000 >on treatment >12,000 > 16,000 >24,000 > 166,000	4 units of platelets, prednisolone 1mg/kg	Not reported
3	Bennett et al. (2020) [14]	73Y female	Fever, shortness of breath, diarrhea, fatigue, body ache, cough. Covid 19 positive	<3000 (undetectable platelets) > on treatment> 105,000 > 146,000	1 unit apheresis platelets, IVIG 1g/kg/day - 2 doses, hydroxychloroquine 400mg	Not reported
4	Sadr et al. (2020) [15]	57Y female	Headache, malaise. Covid 19 positive	48,000 >19,000 on treatment 26,000 > 4000 >144,000		Not reported
5	Nham et al. (2020) [16]	54Y male	Headache, productive cough, myalgia, fever, epistaxis, petechiae.	154,000 >135,000 >113,000 >2000	Lopinavir, levofloxacin, ceftriaxone	Not reported
6	Lorenzo-Villalba et al. (2020) [17]	57Y female	Fever, dry cough, shortness of breath, epistaxis, cutaneous purpura	2000> on treatment> 75,000	IVIG, eltrombopag	Not reported
7	Lorenzo-Villalba et al. (2020) [17]	66Y male	Fever, cough, shortness of breath, diarrhea, epistaxis	73,000 > 1000>on treatment>20,000 > 149,000	IVIG, eltrombopag	Not reported
8	Levraut et al. (2021) [18]	63Y female	Fever, dry cough, headache	197,000 >3000 >on treatment>38,000 > 95,000 > 145,000	IVIG	Not reported