Table 2.

Epigenetic Modulatory Genes: Mixed-Model ANOVAs with Observed and Corrected p-values.

Outcome	Gene Name	Predictor	F	pobserved	pcorrected
AURKC	aurora kinase C	Age	0.04	0.848
		BMI	0.04	0.835
		Group	0.18	0.676	0.779
		Time	0.54	0.465
		Group by Time	1.58	0.213	0.327
DNMT3A*	DNA methyltransferase 3 alpha	Age	14	<.001
		BMI	0.15	0.695
		Group	7.57	0.008	0.027
		Time	0.85	0.361
		Group by Time	3.34	0.073	0.134
HDAC2*	histone deacetylase 2	Age	1.7	0.197
		BMI	1.63	0.206
		Group	1.83	0.181	0.292
		Time	0.79	0.379
		Group by Time	1.15	0.287	0.412
HDAC3*	histone deacetylase 3	Age	0.28	0.599
		BMI	0	0.951
		Group	3.77	0.057	0.117
		Time	0.03	0.862
		Group by Time	0.47	0.497	0.63
HDAC9*	histone deacetylase 9	Age	0.18	0.677
		BMI	1.17	0.283
		Group	15.11	<.001	0.002
		Time	0.14	0.714
		Group by Time	18.53	<.001	0.001
KAT6B	lysine acetyltransferase 6B	Age	0.32	0.576
		BMI	0.12	0.732
		Group	9.88	0.003	0.011
		Time	0.02	0.899
		Group by Time	0.8	0.374	0.504
KAT7	lysine acetyltransferase 7	Age	0.08	0.772
		BMI	0	0.968
		Group	0.09	0.76	0.822
		Time	0.49	0.486
		Group by Time	0.01	0.943	0.957
KMT2G	lysine-specific methyltransferase 2G or SET domain containing 1B (SETDB1)	Age	0.31	0.582
		BMI	3.02	0.087
		Group	23.13	<.001	<.001
		Time	1.17	0.284
		Group by Time	0.48	0.49	0.63
KMT5B	lysine methyltransferase 5B or suppressor of variegation 4–20 homolog 1 (SUV420H1)	Age	0.01	0.915
		BMI	1.6	0.21
		Group	12.13	0.001	0.006
		Time	4.33	0.042
		Group by Time	0.06	0.8	0.851
PRMT5	protein arginine methyltransferase 5	Age	0.06	0.813
		BMI	0.04	0.843
		Group	0.01	0.941	0.957
		Time	0.01	0.921
		Group by Time	15.63	<.001	0.002