Table 1.

Demographics and comorbidities at baseline between the CAD cohort and the age-, sex-, and index date-matched comparison cohort without CAD

	Case (N = 192,367)		Compare (N = 192,367)		p
	n	%	n	%
Year
2008	97,267	50.56	97,564	50.72	0.3382
2009	95,100	49.44	94,803	49.28
Sex
Female	87,140	45.29	87,139	45.29	1
Male	105,227	54.71	105,228	54.71
Age
50–59	80,787	42	80,787	42	1
60–69	57,304	29.79	57,304	29.79
70–79	39,173	20.36	39,173	20.36
80–89	15,103	7.85	15,103	7.85
Baseline comorbidity
Hypertension	14,700	7.64	4633	2.41	< 0.001
Hyperlipidemia	48,616	25.27	16,353	8.5	< 0.001
COPD	35,698	18.56	14,669	7.63	< 0.001
Diabetes mellitus	36,928	19.2	14,898	7.74	< 0.001
PVD	10,668	5.55	3839	2.03	< 0.001
CHF	23,026	11.97	5477	2.85	< 0.001
Stroke	25,245	13.12	10,529	5.47	< 0.001
RA	142	0.07	63	0.03	< 0.001
Morbid obesity	106	0.06	28	0.01	< 0.001
Heart failure	6354	3.3	1557	0.81	< 0.001
Liver cirrhosis	2667	1.39	1938	1.01	< 0.001
CCI
0	110,464	57.42	159,349	82.84	< 0.001
1	25,320	13.16	9318	4.84
2	21,669	11.26	8439	4.39
3	14,693	7.64	5920	3.08
4	9041	4.7	3863	2.01
5	5051	2.63	2220	1.15
6 +	6129	3.19	3258	1.69
Mean (SD)	1.1384 (1.7817)		0.4963 (0.4963)		< 0.001
Mortality	40,089	20.84	46,934	24.4	< 0.001

SD standard deviation, CAD coronary artery disease, COPD chronic lung disease, PVD peripheral vascular disease, CHF congestive heart failure, RA rheumatic arthritis, CCI Charlson Comorbidity Index