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. 2021 May 24;36(4):713–726. doi: 10.1007/s10557-021-07186-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — The numbers of SGLT2 inhibitors and diabetes status with heart failure-related targets are shown in the Venn diagram. There were 13,523 targets of HF from the databases (upper left), 15,291 targets of DM from the database (upper right), 283 targets of HF-DM from studies (bottom left), 135 targets of SGLT2 inhibitors (bottom right) and 125 common targets between SGLT2 inhibitors and diabetes status with heart failure.