Table 2.

Anatomical and functional characteristics stratified by functional pattern of CAD

	Focal (n=51)	Serial lesions (n=20)	Diffuse disease (n=15)	Combination (n=34)	p value
Location, no. (%)
LAD	26 (51)	15 (75)	7 (47)	22 (64)
LCx	12 (24)	3 (15)	3 (20)	6 (18)	0.5
RCA	13 (25)	2 (10)	5 (33)	6 (18)
Pre-PCI quantitative coronary analysis
RVD, mm	2.8 [2.5–3.3]	2.8 [2.3–3.2]	3 [2.4–3.5]	2.9 [2.5–3.4]	0.9
Diameter stenosis, %	60 [52–74]	63 [52–88]	62 [53–66]	57 [52–63]	0.6
Lesion length, mm	14 [9–18]	22 [20–26]	30 [28–37]	19 [15–25]	<0.001
Pre-PCI quantitative flow ratio
QFR, units	0.76 [0.73–0.77]	0.71 [0.66–0.76]	0.75 [0.73–0.76]	0.72 [0.70–0.75]	0.004
ΔQFR vessel, units	0.25±0.05	0.28±0.05	0.23±0.08	0.27±0.05	0.01
Total vessel length, mm	65 [60–72]	65 [60–75]	67 [62–70]	68 [61–75]	0.8
Length with functional disease, mm	10 [5–15]	25 [25–30]	45 [30–55]	40 [33–60]	<0.001
QVPindex, units	0.80±0.09	0.61±0.11	0.38±0.08	0.50±0.10	<0.001
Post-PCI quantitative coronary angiography
Diameter stenosis, %	10 [5–18]	10 [8–20]	12 [8–20]	10 [7–16]	0.9
Total stented length, mm	19 [16–23]	30 [23–37]	33 [28–40]	29 [23–35]	<0.001
Post-PCI quantitative flow ratio
QFR, units	0.98 [0.95–1]	0.94 [0.91–0.96]	0.92 [0.89–0.94]	0.93 [0.87–0.96]	<0.001
QFR value ≤0.89, no. (%)	4 (8)	3 (15)	5 (33)	10 (29)	0.03

LAD left anterior descending, LCx left circumflex, RCA right coronary artery, PCI percutaneous coronary intervention, RVD reference vessel diameter, QFR quantitative flow ratio, ΔQFR delta QFR vessel, QVP_index QFR virtual pullback index