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. 2022 Jul 8;13:3955. doi: 10.1038/s41467-022-31645-1

Fig. 7. PRMT5 depletion effectively blocks tumor cell metastasis to the liver and lung.

Fig. 7

a Bioluminescent imaging of mice tail vein injected SK-N-BE (2) shPRMT5 cells with or without doxycycline treatment (n = 6). b Bioluminescent (upper) and fluorescent imaging (lower) of livers harvested from mice described in a. c Bioluminescent (upper) and fluorescent imaging (lower) of lungs harvested from mice described in a. d FACS analysis of iRFP720+ human neuroblastoma cells in the liver from mice with or without doxycycline treatment (n = 6). e FACS analysis of iRFP720+ human neuroblastoma cells in the lung from mice with or without doxycycline treatment (n = 6). d, e p values were determined by a two-tailed unpaired Student’s t-test using Microsoft Excel. Error bars represent SD.