Table 3.
Adjusted means (95% CI) for other NAFLD-related variables (AST, ALT, GGT) according to the quartiles of organochlorine pesticide subclasses.
| Adjusted Mean (95% CI) (mg/dL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| AST | ALT | GGT | |||||||
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
| p,p'-DDE (ng/g) | |||||||||
| Q1 | 22.67 (21.76–23.62) | 23.76 (22.41–25.2) | 23.49 (22.19–24.87) | 22.2 (21.26–23.17) | 21.79 (20.58–23.07) | 21.56 (20.51–22.67) | 20.27 (18.72–21.95) | 22.47 (19.94–25.33) | 22.28 (19.74–25.16) |
| Q2 | 23.65 (22.65–24.69) | 24.51 (23.12–25.98) | 24.34 (22.92–25.84) | 22.88 (21.64–24.19) | 22.67 (21.53–23.87) | 22.99 (21.9–24.14) | 20.27 (18.69–21.98) | 21.79 (19.68–24.12) | 22.08 (19.96–24.42) |
| Q3 | 23.92 (22.92–24.97) | 24.31 (23.15–25.54) | 24.58 (23.44–25.77) | 23.23 (22.01–24.53) | 23.18 (21.59–24.9) | 23.5 (21.95–25.15) | 22.06 (19.82–24.56) | 22.2 (19.31–25.52) | 21.98 (19–25.42) |
| Q4 | 24.05 (22.87–25.29) | 24.38 (23–25.83) | 24.43 (22.71–26.29) | 21.94 (20.4–23.6) | 22.85 (21.1–24.74) | 22.96 (20.97–25.15) | 21.24 (19.15–23.56) | 21.21 (19.14–23.49) | 21.37 (18.91–24.15) |
| P value | 0.17 | 0.61 | 0.34 | 0.47 | 0.35 | 0.08 | 0.47 | 0.76 | 0.93 |
| Oxychlordane (ng/g) | |||||||||
| Q1 | 22.27 (21.13–23.47) | 22.74 (20.9–24.74) | 22.44 (20.64–24.4) | 21.23 (20.03–22.51) | 20.15 (18.76–21.64) | 19.87 (18.72–21.09) | 17.75 (16.24–19.41) | 18.8 (16.68–21.18) | 18.74 (16.86–20.83) |
| Q2 | 23.64 (22.89–24.41) | 24.53 (23.19–25.94) | 24.22 (22.91–25.6) | 23.61 (22.63–24.64) | 23.51 (22.08–25.03) | 23.26 (21.83–24.77) | 21.62 (19.98–23.38) | 23.23 (21.07–25.6) | 22.67 (20.71–24.82) |
| Q3 | 24.02 (23–25.09) | 24.93 (23.85–26.05) | 25.08 (23.99–26.22) | 23.72 (21.99–25.58) | 24.43 (22.59–26.42) | 25.01 (23.16–27) | 21.81 (19.11–24.88) | 22.67 (19.3–26.64) | 22.92 (19.46–26.98) |
| Q4 | 24 (23.04–25) | 24.98 (23.74–26.3) | 25.43 (24.09–26.85) | 21.04 (19.43–22.8) | 22.78 (21.09–24.61) | 23.33 (21.48–25.34) | 22.45 (19.55–25.77) | 22.94 (19.05–27.63) | 23.46 (19.06–28.86) |
| P value | 0.040 | 0.13 | 0.09 | 0.010 | < 0.001 | < 0.001 | 0.009 | 0.034 | 0.022 |
| Trans-nonachlor (ng/g) | |||||||||
| Q1 | 22.67 (21.67–23.71) | 23.39 (21.73–25.19) | 23.09 (21.68–24.61) | 21.62 (20.42–22.9) | 20.78 (19.21–22.48) | 20.47 (19.27–21.75) | 18.66 (17.13–20.33) | 20.33 (18.28–22.61) | 20.03 (18.14–22.13) |
| Q2 | 23.08 (22.18–24.02) | 24.13 (22.68–25.67) | 24.09 (22.61–25.68) | 22.76 (21.77–23.79) | 23 (21.52–24.58) | 23.24 (21.85–24.72) | 20.36 (18.79–22.07) | 22.09 (20.07–24.32) | 21.72 (19.79–23.83) |
| Q3 | 24.4 (23.57–25.24) | 25.1 (24.08–26.18) | 25.13 (23.94–26.37) | 24.06 (22.59–25.63) | 24.6 (22.84–26.49) | 24.81 (22.88–26.91) | 22.38 (20.5–24.43) | 22.92 (20.15–26.07) | 23.27 (20.4–26.55) |
| Q4 | 24.08 (23.1–25.11) | 24.56 (23.33–25.86) | 24.97 (23.67–26.34) | 21.7 (20.31–23.18) | 22.64 (21.37–24) | 23.3 (21.8–24.9) | 22.83 (20.83–25.03) | 22.17 (19.2–25.6) | 22.73 (19.26–26.82) |
| P value | 0.006 | 0.34 | 0.10 | 0.044 | 0.022 | < 0.001 | 0.010 | 0.48 | 0.23 |
| Mirex (ng/g) | |||||||||
| Q1 | 23.74 (22.73–24.8) | 24.87 (23.21–26.66) | 24.95 (23.19–26.83) | 23.87 (22.81–24.99) | 24.43 (22.75–26.24) | 24.54 (23.03–26.15) | 21.45 (20.29–22.66) | 24.17 (21.82–26.78) | 24.43 (21.67–27.54) |
| Q2 | 22.39 (21.92–22.87) | 23.44 (22.22–24.72) | 23.53 (22.31–24.82) | 21.25 (20.11–22.45) | 21.62 (19.85–23.55) | 21.85 (20.03–23.83) | 17.9 (16.81–19.07) | 19.84 (18.17–21.66) | 20.03 (18.22–22.02) |
| Q3 | 23.41 (22.42–24.44) | 23.75 (22.6–24.96) | 23.91 (22.71–25.17) | 22.73 (21.42–24.13) | 22.3 (21.01–23.68) | 22.58 (21.3–23.94) | 23.15 (21.49–24.94) | 23.3 (21.28–25.51) | 23.11 (20.92–25.52) |
| Q4 | 24.7 (23.93–25.49) | 24.85 (23.95–25.79) | 24.6 (23.63–25.61) | 22.64 (21.36–24) | 22.34 (21.12–23.63) | 22.43 (21.13–23.81) | 21.51 (18.71–24.73) | 20.6 (17.83–23.81) | 20.56 (17.67–23.93) |
| P value | < 0.001 | 0.10 | 0.19 | 0.007 | 0.006 | 0.003 | < 0.001 | < 0.001 | 0.001 |
Model 1: Non-adjusted. Model 2: Adjusted for age, sex, race. Model 3: Adjusted for model 2 and poverty income ratio, smoking, drinking, physical activity.
Subjects were divided into four categories (Q1 to Q4), ranging from the lowest quartile group to the highest quartile group.
AST aspartate transaminase, ALT alanine transaminase, GGT gamma-glutamyl transferase, CI confidence interval.