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. 2022 Jun 22;7(6):582–596. doi: 10.1016/j.jacbts.2022.02.008

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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RNA Sequencing Results

(A) Heat map of RNA sequencing data showing altered gene profiles in whole-kidney tissues from CHF rats with and without RTX treatment along with sham. Kidney injury molecule 1 (Kim1; a specific proximal tubular damage marker) was increased in whole-kidney tissues of CHF rats, which was largely prevented by RTX. (B) Venn diagram highlighting the number of genes differentially expressed between CHF/Sham and CHF/CHF-RTX. (C) Table showing the common genes changed between different comparisons and the fold change. Sham group: n = 5; CHF+Veh group: n = 3; CHF+RTX group: n = 3. Dn = down; other abbreviations as in Figure 1.