Anatomic and enhancement-based assessment methods on axial-view images.
(A) Baseline arterial enhanced T1-weighted MRI scan,
preprocedural for anatomic orientation. (B) One-dimensional
measurement of the largest overall tumor diameter illustrated by a red
line. (C) One-dimensional measurement of the largest
enhancing tumor diameter illustrated by a red line. Enhancement was
defined as hyperintense areas at the arterial phase that were not
visible at the precontrast phase. (D) Semiautomated
three-dimensional tumor and whole-liver segmentation to create a
segmentation mask, which involves the entire lesion and liver. The fine
red line outlines the tumor, and the thick orange line marks the liver
contour. (E) Three-dimensional segmentation mask represents
the total tumor volume in red at maximum intensity projection.
(F) Automatically generated three-dimensional
quantification of enhancing tumor volume based on image subtraction. A
region of interest (green box) was placed on extratumoral liver
parenchyma in the closest proximity to the tumor as a reference to
calculate the relative enhancement values within the tumor. Color coding
varied from red, representing maximum enhancement, to blue, representing
no enhancement.